4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16662 | Tetraethylene glycol | PROTAC Linker 18 | Others |
Tetraethylene glycol (PROTAC Linker 18) is a polyethylene glycol (PEG)-based linker that finds utility in the synthesis of PROTACs[1]. | |||
T17133 | Tos-PEG4-t-butyl ester | Tos-PEG4-Boc | Others |
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition. This compound plays a crucial role in the synthesis of a range of PROTACs, including BI-3663, a highly selective PTK2/FAK PRO... | |||
T17543 | BI-3663 | Others | |
BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation. BI-3663 inhibits PTK2 with an IC50 of 18 nM. BI-3663 is a PROTAC that composes of BI-4464 linked to Pomalido... | |||
T83933 | CST 905 | ||
CST 905, a selective and potent BRAFV600EDegrader (PROTAC) with a DC50 of 18 nM, features a von Hippel Lindau (VHL) E3 ligase ligand connected via a linker to a PLX-derived ligand. Distinctively, CST 905 does not activat... |